Tramadol is a well-known pain relief medication in the world. It is an effective narcotic pain-relieving medication. This drug is mostly prescribed for treating moderate or moderately severe pain in adults. This drug is a synthetic analog of codeine which has a less potential to cause addiction and for abuse than any other opioid agonists.
Tramadol is also known for treating different types of pain. Pain used to arise due to various reasons and Tramadol is one of the effective drugs that can be used for treating most of them.
The different types of pain have been listed below,
- Nociceptive Pain
- Neuropathic Pain
- Back Pain
As you know, that each type of pain would have a different origin, so does these types have an optimal treatment strategy. Pain often results in the trigger that occurs in the brain cells. The signal gets transmitted from the muscle nerve to the brain thus makes one experience pain in that particular part. As these, brain cells lead to the sensation of pain, they have the ability to modulate the strength and the effect of pain signals.
You would have experienced that having a physical injury without the sensation of pain (nociceptive pain) and at some time, you would feel the pain where there is the absence of physical injury (central pain). This is due
to the factors like mood, context, and attention that we give to an injury that triggers the sensation of pain.
Tramadol and Nociceptive Pain
Nociceptive pain is caused by the tissue damage. This pain used to occur and would be felt as sharp, aching or throbbing pain in the body. The sensation of the pain would be triggered when the damaged tissues recruit
many inflammatory and immune cells to repair the damage occurred area. Calling of these cells would release the chemicals that activate the receptors on the nerves which would make a way into the spinal cord and end up in the brain. The use of Tramadol would help to ease the pain, such that the effects are similar to the intake of morphine or cannabis.
Nociceptive pain will be weakened with the use of pain relief medication which used to work effectively on the areas of occurred injury. The working involves the blocking the inflammatory process or the signals will be transmitted and also have to damp the signals that reduced their way up to the spinal cord to the brain. Tramadol would help in both the process to reduce the pain sensation.
Tramadol for Neuropathic Pain
Neuropathic pain used to arise in the body’s nervous system. This is one of the common pain that can be experienced by many people. Usually, Neuropathic pain affects around 7-10% of the world’s population that includes the suffering by stabbing, pinching or another forceful injury that damages the nerves. Treating of Neuropathic pain is difficult, it is because it doesn’t have the inflammation that can be targeted by non-steroidal anti-inflammatory drugs like ibuprofen. However, Buying Tramadol was recommended by many physicians to treat the pain sensation in the body. It is one of the promising options which helps to maintain the ease over the damage or injury occurred area.
Tramadol for Back Pain
Another use of Tramadol is that this medication is very effective in treating back pain. This drug releases the chemicals in the brain and this one will start to get over with the pain simply. This medication is widely prescribed for this back pain condition. Generally, back pain may result in spinal diseases such as arachnoiditis, epidural fibrosis, lumbar disc herniation, osteoporosis, and spinal stenosis. The pain used to occur in the lower back and it might extend to thighs, calves and even to your feet. Tramadol intake as per the prescribed dosage will help to ease from the cause of pain in the body.
- Oliva P, Aurilio C, Massimo F, Grella A, Maione S, Grella E, Scafuro M, Rossi F, Berrino L. The antinociceptive effect of tramadol in the formalin test is mediated by the serotonergic component. Eur J Pharmacol. 2002;445(3):179–185. doi: 10.1016/S0014-2999(02)01647-3. [PubMed] [CrossRef]
- Newton J, Scott C, Edwards C, et al. Clinical Standards Advisory Group. Services for patients with pain. London: The Stationery Office, 1999.
- Duhmke RM, Cornblath DD, Hollingshead JR.Tramadol for neuropathic pain. [Cochrane Database Syst Rev. 2006]
- Finnerup NB, et al. Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis. Lancet Neurol. 2015;14:162–173. This systematic review updates the recommendations for the pharmacological management of neuropathic pain, emphasizing that modest efficacy, considerable placebo responses, heterogeneous diagnostic criteria and poor phenotypic profiling account for moderate trial outcomes and unmet needs of the patients. [PMC free article] [PubMed]
- Dias QM, et al. The effect of intrathecal gabapentin on neuropathic pain is independent of the integrity of the dorsolateral funiculus in rats. Life Sci. 2012;91:837–842. [PubMed]
- Chang JK, Yu CT, Lee MY, Yeo K, Chang IC, Tsou HK, et al. Tramadol/acetaminophen combination as add-on therapy in the treatment of patients with ankylosing spondylitis. Clin Rheumatol. 2013 Mar;32(3):341–347. [PubMed] [Reference list]
- Park KS, Choi JJ, Kim WU, Min JK, Park SH, Cho CS. The efficacy of tramadol/acetaminophen combination tablets (Ultracet®) as add-on and maintenance therapy in knee osteoarthritis pain inadequately controlled by nonsteroidal anti-inflammatory drug (NSAID) . Clin Rheumatol. 2012 Feb;31(2):317–323. [PubMed] [Reference list]