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How Long Does Tramadol Stay In Your System – Dr. Adrian G Bartoli’s Report

Tramadol Stay In Your System

Tramadol comes under the synthetic analgesics, which is used in the treatment of moderate to severe pain in users. There are several brand names for this pain killer and some of them are ConZip, Synapyrn, Ryzolt, Rybix and Ultram. As far as Tramadol is concerned, it is always recommended that you consult a doctor to get to know about the effects and dosage. However, for precautions with medicationl usage, understanding how Tramadol acts in your body or how long it stays in the body will be essential to avoid drug interactions and any form of abuse. In case if you buy Tramadol from reliable online dispensary and going to be used in children, then it needs a special concern, which you can always discuss with your doctor.

How Tramadol acts in your body

Tramadol brings about pain relief by acting on the pain receptors of the brain so that the reuptake of serotonin and norepinephrine is inhibited. The pain relief mechanism usually starts in an hour after the Tramadol dose has been consumed, while the effects intensify in two to four hours on an average. There are also extended release versions for Tramadol, where the medication stays in the system for a long time and just a single pill is needed for that purpose.

This pain killer causes pupil contraction and also breathing depression when the mechanism action is active. The mobility in the stomach is affected that digestion takes longer than expected leading to constipation. You might also experience blood vessels dilation, flushing, irritation, itching and also dizziness when you tend to get up suddenly after lying down for a long time. The breakdown of Tramadol usually occurs in the liver and it is excreted through urine. But some people’s system might not be efficient metabolizers of this medication and hence it could take long time for the process of breakdown. In people, who have poor metabolism, consumption of other medications can lead to potential risks in the body.

Tramadol displays an half-life between five to nine hours or it could even be longer in people who consume Tramadol doses multiple times. The elimination of the medication from the body takes the same time as the half-life for complete evacuation.

It is an addictive medication even if it is used in limited doses. Hence, it might display some withdrawal symptoms when it is stopped all of a sudden. Hence, consult your doctor when you plan to stop using Tramadol for your doctor might chart a course plan for the same without any potential effects.

Avoiding Tramadol Overdose and Risky Interactions

Tramadol must be consumed as per the prescribed dosages by following the guidelines carefully. Also, Tramadol medications must not be cut, divided or broken down, especially in extended release tablets, as that would mean a larger dose will be released.

Tramadol interacts with a lot of medications out there and at times, it can even lead to serious consequences if not attended to properly. In these cases, please talk to a doctor and get to know the drugs that could possibly interact with Tramadol in the long run. Also, inform your doctor about all the drugs you have been consuming on a regular basis so that the doctor could assess your situation better. Tramadol causes life threatening interaction with benzodiazepines and MAO inhibitors. So, please make sure that you show a special concern when you consume Tramadol with these drugs. Also, avoid using alcohol and other street drugs with Tramadol as it can cause serious implications.

Tramadol overdose is evident even in normal doses and it can cause certain potential symptoms in the body that needs to be informed to a doctor immediately for timely assistance. Some of the symptoms of Tramadol overdose are:

  • Decrease in the size of the pupil
  • Breathing difficulties
  • Dizziness
  • Lack of Consciousness
  • Coma
  • Slower heartbeat rate
  • Weakness in the Muscles


To determine how long Tramadol stays in your body, you will have to weigh in various variables like metabolism, body mass, age, gender, hydration, medical history, and other such factors. Tramadol can generally be detected in the urine for two to four days on an average. It really doesn’t show up positively in the opiate screening tests, but it is detectable with a prescription drug screening test. For efficient interpretation, you can always reveal the Tramadol prescription to the lab if you are going in for a urine drug test to avoid certain confusions.

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